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Medications
Used in Respiratory Pharmacology |
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The goal of respiratory
pharmacology is to prevent or relieve the pathologic triad discussed
at the beginning of this CEU module: bronchospasm, airway inflammation
or mucosal edema, and retained secretions. The medicating agents used
to relieve these symptoms can be referred to as the "treatment triad."
The pathologic triad and treatments include: |
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Pathologic Condition
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Treatment
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Bronchoconstriction
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Bronchodilator (eg.,
albuterol)
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Airway edema
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Decongestant (eg., recemic
epinephrine)
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Retained secretions
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Hydration or mucolytics
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The actions of the various
categories of pharmacologic agents used to relieve the pathologic triad
can be briefly summarized as:
Bronchodilators
increase airway patency by relaxing the bronchial muscle spasm triggered
by disease or irritation.
Decongestants
cause contraction of the muscle fibers of the arterioles and small
arteries, triggering a reduction of blood flow to the affected area
and lowering of hydrostatic pressure that permits fluid to move
into the tissues.
Mucokinetics
facilitate loosening and mobilization of secretions.
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